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So, it could be that the effect is all in your head. It could be that the effect is real, whether it’s placebo pain relief or measurable weight loss. But either way, if your experience flies in the face of research results, you’re probably going to go with your experience. And Hitchcock says that could be a completely rational decision. If the cost of continuing (say, paying for a supplement) is small compared to the risk of discontinuing (and potentially giving up the perceived benefit), it makes sense to keep on keeping on.

https://www.washingtonpost.com/lifestyle/food/when-it-comes-to-nutrition-were-all-too-eager-to-ignore-the-evidence-heres-why/2020/02/23/d4dd8534-54a8-11ea-9e47-59804be1dcfb_story.html

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